BeOne Medicines AG (ONC) Stock Analysis
Healthcare · Biotechnology · NasdaqGS
BeOne Medicines AG (ONC) posted $5.34B in revenue for fiscal 2025 (up 40.2% year over year), at a 5.4% net margin, and has compounded revenue about 76.8%/yr over five years, per its SEC filings.
Data last refreshed August 2, 2026 from SEC filings · how we compute this
The analyst's take on BeOne Medicines AG
BeOne Medicines AG has grown revenue from $1.07M to $5.34B over the last 10 fiscal years, compounding about 76.8% a year. The most recent year was up 40.2%, so growth has cooled from its longer-run pace.
Net margin sits at 5.4%, up 22.3 points year over year on a 87.5% gross margin. It carries about $1.02B of total debt.
At today's valuation the market is pricing in roughly 13.8% annual free-cash-flow growth.
Synthesised from BeOne Medicines AG's SEC filings — descriptive, not advice. Ask the analyst your own question →
BeOne Medicines AG revenue & earnings — last 10 fiscal years
| Metric | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $1.07M | $238.39M | $198.22M | $428.21M | $308.87M | $1.18B | $1.42B | $2.46B | $3.81B | $5.34B |
| Gross profit | — | $233.41M | $169.51M | $357.02M | $238.22M | $1.01B | $1.13B | $2.08B | $3.22B | $4.67B |
| Net income | $-119.22M | $-93.11M | $-673.77M | $-948.63M | $-1.62B | $-1.46B | $-2.00B | $-881.71M | $-644.79M | $286.93M |
| Net margin | -11141.8% | -39.1% | -339.9% | -221.5% | -526.1% | -123.9% | -141.5% | -35.9% | -16.9% | 5.4% |
Source: BeOne Medicines AG SEC filings (10-K). 12 years of history available in the interactive view.
BeOne Medicines AG: no obvious red flags in the filings
Our deterministic scan of the filed statements — receivables vs sales, earnings vs cash, dilution, leverage and margins — didn't flag anything. Ask about the risks →
What growth is priced into ONC stock?
At today's market cap of $27.04B, BeOne Medicines AG is priced for free-cash-flow growth of about 13.8% per year for 10 years (assuming a 10% discount rate and 2.5% terminal growth, base FCF $861.05M from the FY ending 2025-12-31). For comparison, revenue 76.8%/yr, computed from its SEC filings. This is a reverse DCF — a translation of the price into a growth assumption you can judge, not a fair value and not advice. Change the assumptions yourself in the interactive view →
Explore 12 years of BeOne Medicines AG financials — interactive
Full income statement, balance sheet and cash flow with CAGR and trend on every row, 48 quarters, valuation ratios, plain-English health checks, and Ask — our SEC-grounded research assistant.
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BeOne Medicines AG financial history by metric
About BeOne Medicines AG
BeOne Medicines AG, an oncology company, engages in discovering and developing various treatments for cancer patients in the United States, China, Europe, and internationally. The company's commercial stage products include BRUKINSA, a small molecule inhibitor of Bruton's Tyrosine Kinase (BTK) for the treatment of various blood cancers; TEVIMBRA, an anti-PD-1 antibody immunotherapy for the treatment of various solid tumor and blood cancers; SYLVANT for the treatment of adult patients with multicentric castleman disease; BAITUOWEI for patients with BC in premenopausal and perimenopausal women, and cancer; and PARTRUVIX for the treatment of various solid tumors. Its clinical stage products comprise Sonrotoclax BGB-11417, a small molecule Bcl-2 inhibitor; BGB-16673, a BTK targeting chimeric degradation activation compound active against wild type and mutant BTK; BG-60366, an EGFR-targeted CDAC; BG-89894 (SYH2039), a MAT2A Inhibitor; BGB-58067, an MTA-Cooperative PRMT5 Inhibitor; BG-T187 and BG-C0902, an anti-EGFRxMET trispecific antibody; BGB-26808, a HPK-1 Inhibitor; BGB-C354, an anti-B7H3 ADC; Zanidatamab, a bispecific HER2-targeted antibody; BG-C137, an anti-FGFR2b ADC; BGB-53038, a Pan-KRAS Inhibitor; BGB-B2033, an anti-GPC3x4-1BB bispecific antibody; BGB-B3227, an anti-MUC1xCD16A bispecific antibody; BG-C477, an anti-CEAADC; BGB-43395, a CDK4 Inhibitor; BG-68501, a CDK2 Inhibitor; BG-C9074, an anti-B7H4 ADC; BGB-21447, a Bcl-2 Inhibitor; and BGB-45035, an IRAK4-targeted CDAC. It also has various preclinical programs. The company has agreements Amgen, BMS, Bio-Thera, EUSA Pharma, Luye Pharmaceutical, and Novartis. The company was formerly known as BeiGene, Ltd. and changed its name to BeOne Medicines AG in May 2025. BeOne Medicines AG was founded in 2010 and is based in Basel, Switzerland.
BeOne Medicines AG — frequently asked questions
What is BeOne Medicines AG's revenue?
BeOne Medicines AG (ONC) reported revenue of $5.34B for fiscal year 2025, up 40.2% from the prior year, according to its SEC filings.
Is BeOne Medicines AG profitable?
Yes. ONC earned net income of $286.93M in fiscal 2025, a net margin of 5.4%.
What is ONC's P/E ratio?
BeOne Medicines AG trades at a price-to-earnings ratio of about 58.8 based on the latest data in our nightly-refreshed cache.
How fast is BeOne Medicines AG growing?
ONC's revenue grew at roughly 76.8% per year over the last five fiscal years (compound annual growth rate), computed from SEC-filed statements.
How much debt does BeOne Medicines AG have?
As of fiscal year 2025, ONC carried roughly $1.02B in total debt (short- plus long-term borrowings), per its filed balance sheet.
What is BeOne Medicines AG's gross margin?
ONC's gross margin was 87.5% in fiscal 2025 — gross profit of $4.67B on revenue of $5.34B.
What is BeOne Medicines AG's market cap?
BeOne Medicines AG (ONC) has a market capitalization of about $27.04B, based on the latest data in our nightly-refreshed cache.
When does BeOne Medicines AG's fiscal year end?
ONC's fiscal year ends in December. Its most recent annual filing covers the fiscal year ending 2025-12-31.
What growth is priced into ONC stock?
At today's market cap of $27.04B, BeOne Medicines AG is priced for free-cash-flow growth of about 13.8% per year for 10 years (assuming a 10% discount rate and 2.5% terminal growth, base FCF $861.05M from the FY ending 2025-12-31). For comparison, revenue 76.8%/yr, computed from its SEC filings.
Where does this data come from?
All figures are computed from BeOne Medicines AG's official SEC filings (10-K and 10-Q), covering 12 years of history, refreshed nightly. stockportfolio.pro does not provide investment advice.