Harmony Biosciences Holdings, Inc. (HRMY) Stock Analysis
Healthcare · Biotechnology · NasdaqGM
Harmony Biosciences Holdings, Inc. (HRMY) posted $868.45M in revenue for fiscal 2025 (up 21.5% year over year), at a 18.3% net margin, and has compounded revenue about 40.3%/yr over five years, per its SEC filings.
Data last refreshed August 2, 2026 from SEC filings · how we compute this
The analyst's take on Harmony Biosciences Holdings, Inc.
Harmony Biosciences Holdings, Inc. has grown revenue from $6.00M to $868.45M over the last 7 fiscal years, compounding about 40.3% a year. The most recent year was up 21.5%, so growth has cooled from its longer-run pace.
Net margin sits at 18.3%, down 2.1 points year over year on a 77.2% gross margin. It carries about $163.66M of total debt.
At today's valuation the market is pricing in roughly -9.6% annual free-cash-flow growth. The one thing worth a second look in the filings is net margin shrinking.
Synthesised from Harmony Biosciences Holdings, Inc.'s SEC filings — descriptive, not advice. Ask the analyst your own question →
Harmony Biosciences Holdings, Inc. revenue & earnings — last 7 fiscal years
| Metric | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|
| Revenue | $6.00M | $159.74M | $305.44M | $437.86M | $582.02M | $714.73M | $868.45M |
| Gross profit | $4.42M | $132.00M | $249.92M | $354.37M | $460.79M | $557.92M | $670.11M |
| Net income | $-151.98M | $-36.94M | $34.60M | $181.47M | $128.85M | $145.49M | $158.69M |
| Net margin | -2535.1% | -23.1% | 11.3% | 41.4% | 22.1% | 20.4% | 18.3% |
Source: Harmony Biosciences Holdings, Inc. SEC filings (10-K).
Harmony Biosciences Holdings, Inc.: 1 potential red flag in the filings
Patterns in the filed statements worth a second look — computed and cited, not AI guesswork, and not a signal to sell. The kind of thing that hides in a 10-K.
- Net margin shrinkingNet margin fell from 41.4% to 18.3% over ~3 years — profitability is compressing.
What growth is priced into HRMY stock?
At today's market cap of $2.05B, Harmony Biosciences Holdings, Inc. is priced for free-cash-flow growth of about -9.6% per year for 10 years (assuming a 10% discount rate and 2.5% terminal growth, base FCF $347.89M from the FY ending 2025-12-31). For comparison, revenue 40.3%/yr, computed from its SEC filings. This is a reverse DCF — a translation of the price into a growth assumption you can judge, not a fair value and not advice. Change the assumptions yourself in the interactive view →
Explore 7 years of Harmony Biosciences Holdings, Inc. financials — interactive
Full income statement, balance sheet and cash flow with CAGR and trend on every row, 48 quarters, valuation ratios, plain-English health checks, and Ask — our SEC-grounded research assistant.
Open the interactive view — freeOr start a 7-day free trial to track HRMY in your portfolio →
Harmony Biosciences Holdings, Inc. financial history by metric
Compare Harmony Biosciences Holdings, Inc. with peers
About Harmony Biosciences Holdings, Inc.
Harmony Biosciences Holdings, Inc., a commercial-stage pharmaceutical company, focuses on developing and commercializing therapies for patients with rare neurological diseases in the United States. The company offers WAKIX (pitolisant), a molecule with a novel mechanism of action for the treatment of excessive daytime sleepiness in adult patients with narcolepsy. It also develops Pitolisant that is in Phase 3 clinical trial for the treatment of Prader-Willi Syndrome (PWS); in Phase 2 clinical trial to treat Myotonic Dystrophy (DM1); and is in Phase 2 clinical trials for the treatment of Pitolisant Gastro-Resistant (GR) and Pitolisant High-Dose (HD). In addition, the company's products under development include BP1.15205, an orexin 2 receptor agonist for the treatment of narcolepsy and other potential indications; and HBS-102, a melanin-concentrating hormone receptor type 1 (MCHR1) antagonist. Further, it develops ZYN-002 that is in a Phase 3 registrational trial for the treatment of Fragile X Syndrome; and 22q Deletion Syndrome, a disorder caused by a small missing piece on the long arm of the 22nd chromosome. Additionally, the company is developing EPX-100 (clemizole hydrochloride), a serotonin (5HT-2) receptor agonist to treat dravet syndrome and lenox-gastaut syndrome; EPX-200 (liquid formulation of lorcaserin), a selective 5HT-2C agonist to treat developmental and epileptic encephalopathies; CBS105 for the treatment-resistant narcolepsy; and CBS104 for refractory epilepsy. The company was formerly known as Harmony Biosciences II, Inc. and changed its name to Harmony Biosciences Holdings, Inc. in February 2020. Harmony Biosciences Holdings, Inc. was incorporated in 2017 and is headquartered in Plymouth Meeting, Pennsylvania.
Harmony Biosciences Holdings, Inc. — frequently asked questions
What is Harmony Biosciences Holdings, Inc.'s revenue?
Harmony Biosciences Holdings, Inc. (HRMY) reported revenue of $868.45M for fiscal year 2025, up 21.5% from the prior year, according to its SEC filings.
Is Harmony Biosciences Holdings, Inc. profitable?
Yes. HRMY earned net income of $158.69M in fiscal 2025, a net margin of 18.3%.
What is HRMY's P/E ratio?
Harmony Biosciences Holdings, Inc. trades at a price-to-earnings ratio of about 14.3 based on the latest data in our nightly-refreshed cache.
How fast is Harmony Biosciences Holdings, Inc. growing?
HRMY's revenue grew at roughly 40.3% per year over the last five fiscal years (compound annual growth rate), computed from SEC-filed statements.
How much debt does Harmony Biosciences Holdings, Inc. have?
As of fiscal year 2025, HRMY carried roughly $163.66M in total debt (short- plus long-term borrowings), per its filed balance sheet.
What is Harmony Biosciences Holdings, Inc.'s gross margin?
HRMY's gross margin was 77.2% in fiscal 2025 — gross profit of $670.11M on revenue of $868.45M.
What is Harmony Biosciences Holdings, Inc.'s market cap?
Harmony Biosciences Holdings, Inc. (HRMY) has a market capitalization of about $2.05B, based on the latest data in our nightly-refreshed cache.
When does Harmony Biosciences Holdings, Inc.'s fiscal year end?
HRMY's fiscal year ends in December. Its most recent annual filing covers the fiscal year ending 2025-12-31.
What growth is priced into HRMY stock?
At today's market cap of $2.05B, Harmony Biosciences Holdings, Inc. is priced for free-cash-flow growth of about -9.6% per year for 10 years (assuming a 10% discount rate and 2.5% terminal growth, base FCF $347.89M from the FY ending 2025-12-31). For comparison, revenue 40.3%/yr, computed from its SEC filings.
Where does this data come from?
All figures are computed from Harmony Biosciences Holdings, Inc.'s official SEC filings (10-K and 10-Q), covering 7 years of history, refreshed nightly. stockportfolio.pro does not provide investment advice.